Fertility is a journey, and navigating the vast array of supplements available can be overwhelming. As a Fertility Dietitian in the UK, I often get asked about the best fertility supplements and prenatal vitamins. In this blog, we provide evidence-based recommendations and answer ‘what are the best fertility supplements for women’ to help you make informed decisions. We cover prenatal supplements, coenzyme Q10, omega-3 supplements and more.
Let’s dive in!
The best prenatal vitamins for fertility
If you’re trying to conceive, a high-quality prenatal supplement is one of the best investments you can make. Prenatal supplements are multivitamins that contain essential nutrients to support fertility. They are designed to support a woman’s chances of pregnancy success. While optimising diet for fertility should always be priority number one, evidence shows that taking a prenatal supplement alongside a fertility-supporting diet can significantly boost your chances of conception (1).
Even if you have a good fertility-supporting diet, a prenatal supplement can:
- Reduce Nutrient Deficiencies: Prenatal supplements help cover any nutritional gaps, lower levels of certain nutrients are linked to unexplained infertility and increased time to pregnancy.
- Strengthen Antioxidant Defences: They protect eggs from damage.
- Reduce Ovulatory Problems: Ovulatory issues are a common cause of infertility, and supplements can help reduce the risk of these (2).
- Support AMH Levels: Anti-Müllerian Hormone (AMH) levels, a marker of ovarian reserve, can be supported with the right nutrients. This is particularly helpful if you are trying to conceive after the age of 35 (3).
When to take fertility supplements
It is best to take fertility supplements for 3 months before conception. This is because it takes eggs around 3 months to grow and mature, taking supplements during this process allows your antioxidant defences to build up and supports your egg quality as they develop. Additionally, 3 months allows you time to correct any nutritional deficiencies and get used to taking your supplement daily.
Choosing the best prenatal vitamins for women
With many products on the market, it’s important to choose one that fits your needs. Here’s what to look for in your conception vitamins:
- Vitamin D: Lower levels are associated with infertility (4). Ensure your supplement contains at least 10mcg.
- Folate or Folic Acid: Critical for DNA production, egg quality, and implantation (5). Look for at least 400mcg.
- Antioxidants: Look for vitamins C, E, and selenium to combat oxidative stress (6).
- Zinc: Essential for the egg maturation process (7).
- Iodine: Important for thyroid function and reducing the risk of unexplained infertility (8).
- B Vitamins: Vitamins B12 and B6 are crucial, as insufficient levels are common in infertile women (9).
What are the best fertility supplements for women?
Disclosure: All supplement recommendations in this guide are based on clinical expertise and current fertility nutrition research. Some links are affiliate-based, but this does not influence which products are included. Discount codes are offered for your benefit, with no added cost to you.
| Supplement | Best For | Why | Discount |
|---|---|---|---|
| Proceive Women | Under 35, early in TTC journey. | Balanced, high-quality formula with methylfolate. Good everyday coverage | DIETITIANRO15 – 15% off |
| Proceive Max Women | 35+, or TTC for 12+ months. | Higher nutrient levels for broader coverage. Sachet format. | DIETITIANRO15 – 15% off |
| Wild Nutrition Fertility Support | Those preferring food-grown formats. | Whole-food based, sustainably sourced. | HABIT50 – 50% off their first 3 months of subscription WILDCARE-N27-20 – 20% off for a standalone purchase. |
| Zita West Vitafem | Women seeking a premium, clinic-developed option | Fertility expert brand, created alongside IVF specialists. Provides a broad mix of nutrients. | |
| OVUM | Those looking for a doctor-formulated, antioxidant-led blend. | Strong antioxidant profile | DIETITIANRO – 15% off |
| Artah Core Prenatal | Those wanting fertility support alongside a daily wellness multi. | Wide range of nutrients with added antioxidants like CoQ10 and NAC. | RoHuntrissNutrition – 15% off |
| Pregnacare | Budget-conscious and widely available option. | Covers the basics and uses folic acid rather than methylfolate. |
Pregnacare vs Proceive
Proceive and Pregnacare are both prenatal supplement ranges designed to support reproductive and pregnancy health. Proceive Women is a higher-dose, amino-acid–rich formula with a broad range of nutrients (including active folate, CoQ10, and amino acids) designed to strongly support ovarian function, egg quality, and hormonal balance.
Pregnacare Conception is a more standard multivitamin-style fertility support with key nutrients like folic acid, zinc, vitamin D, and antioxidants in moderate, RDA-based levels. Which you choose may depend on your age and how long you have been trying to conceive, the form you prefer to take your supplements in (sachet versus tablets) as well as your budget constraints. Both contain a wide range of fertility-supporting nutrients. Pregnacare contains folic acid, while Proceive contains methylfolate. Either could be considered as one of the best fertility supplements for women, what you choose depends on your unique needs.
Methyl folate vs folic acid
Prenatal supplements should always contain vitamin B9. Vitamin B9’s natural form is methylfolate, and its synthetic form is folic acid. A risk factor for neural tube defects is having low folate levels. Both forms increase blood folate levels, which corrects the risk factor of folate deficiency, but currently, public health guidance recommends only folic acid to reduce the risk of neural tube defects. If your prenatal supplement contains methylfolate, you can safely add 400 mcg of folic acid, such as Vitabiotics Ultra Folic acid (400mcg), as a standalone supplement to ensure you have both forms. We would recommend discussing this with your healthcare provider if you have questions. The best folic acid supplements contain 400mcg of folic acid.
Methylfolate may be considered in some situations, for example, people who carry a mutation in the MTHFR gene may not be able to convert folic acid to the active form of folate in the body as efficiently as those without the mutation (10). There is also some evidence to suggest that methylfolate could be explored in cases of recurrent miscarriage or recurrent implantation failure. However, you should discuss this with your healthcare provider to understand what form is best for your fertility supplement regimen. Please be aware that this information is not a substitute for individualised medical advice.
| Supplements | Best for | Why | Discount |
|---|---|---|---|
| Together Health Folate | Those wanting a straightforward 400 µg folate to add to their regimen | Provides 400 µg folate in the form of 5 MTHF | |
| Vitabiotics Folic Acid (400µg with 5 µg B12) | Reduces the risk of neural tube defects. Can be added alongside a prenatal supplement containing methylfolate. | Provides 400 µg folic acid (as per UK advice) |
Our other top fertility supplement recommendations
For some people, tailored standalone supplements can support their fertility journey alongside a prenatal supplement. Here are our top recommendations to help you on your fertility journey.
CoQ10 for female fertility
If you are over the age of 35, adding a coenzyme Q10 supplement to your regimen can be one of the best fertility supplement choices you can make as a woman. CoQ10 is crucial for energy production and can help support egg production, maturation, and quality (11). Many prenatal supplements contain a small amount of coenzyme Q10; however, evidence shows us that taking coenzyme Q10 as a standalone supplement at a higher dose can improve egg and embryo quality and the outcomes of IVF. Check out our blog if you want to learn more about CoQ10.
| Supplements | Best for | Why | Discount |
|---|---|---|---|
| Zita West Kaneka Ubiquinol | Those preferring the active, body-ready form of CoQ10. | Provides 200 mg Kaneka Ubiquinol. | |
| MicroCell CoQ10 | Those looking for a straightforward, high-dose CoQ10. | Provides 200 mg Ubiquinone, the standard form of CoQ10. | DR25 – £25 off any orders over £249 |
Myo-inositol supplements for PCOS and IVF
Myoinositol is one of the best fertility supplements for women with PCOS. It helps regulate menstrual cycles, restore ovulation, improve egg and embryo quality, and enhance clinical pregnancy rates (12). With regards to doses, 4g/day of myo-inositol alone or a combination of myo-inositol and d-chiro inositol in a 40:1 ratio can support outcomes.
A myoinositol supplement could also support IVF patients. It has been shown to increase clinical pregnancy rate in women undergoing IVF by improving egg and embryo quality and improving response to ovarian stimulation (13).
| Supplements | Best for | Why | Discount |
|---|---|---|---|
| Zita West inositol and folate | Those wanting a straightforward myo-inositol and folate blend. | Provides 4 g myo-inositol with 200 mcg methyl folate only. | |
| Proceive Pure Myoinositol | For those looking for a straightforward myoinositol | Provides 4 g myo-inositol alone | DIETITIANRO15 – 15% off |
The best omega-3 supplements for fertility
Omega-3 fatty acids (EPA and DHA) are essential fats that must be consumed through diet or supplements. They are beneficial for supporting egg quality and improving outcomes for natural conception and IVF, and so are an important consideration when choosing the best fertility supplements for you (14). Omega-3 supplements are particularly important if you do not consume 1-2 portions of oily fish (salmon, makerel or sardines) weekly. Research indicates that even those who consume omega-3 through food can benefit from supplementation.
We’d recommend adding an omega-3 supplement if your prenatal doesn’t already include it (they generally don’t). Omega-3 supplements are generally derived from fish oil, however there are vegan options derived from algal oil on the market as well.
| Supplements | Best for | Why | Discount |
|---|---|---|---|
| Wild Nutrition Food-Grown Pure Strength Omega 3 | Those looking for natural, whole foods, strong EPA + DHA supplement. | Provides a total of 1200 mg EPA and DHA from fish oil in a food-grown format. | HABIT50 – 50% off their first 3 months of subscription WILDCARE-N27-20 – 20% off for a standalone purchase. |
| Proceive omega 3 | Those who want a high-quality omega-3 | Provides 1100 mg EPA and DHA. | DIETITIANRO15 – 15% off |
| Zita West – Vital DHA | Those wanting a higher DHA ratio. | Provides 1072 mg omega-3 with a balance of 50% DHA and 10% EPA, designed with fertility and pregnancy in mind. | |
| Zita West Ultra Omega 3 | Those wanting a lighter omega-3 supplement. | Provides 450 mg EPA and DHA, a lower-strength choice |
How to choose the best fertility supplements for women
Let’s round up all the things you should be thinking about when choosing the best fertility supplements for you.
- Does your prenatal supplement contain vitamin D (at least 10mcg) and 400mcg of folic acid or methylfolate? These are the bare essentials; even if you weren’t taking a multivitamin fertility supplement, you should not be avoiding vitamin D and folic acid.
- Does your prenatal cover all of the important fertility supporting nutrients – does it contain the important nutrients and antioxidants – selenium, zinc, iodine, vitamin B12, vitamin C and E?
- Do you need extra support on top of your prenatal? For example, the addition of coenzyme Q10 or omega-3?
- Is what you are taking the best option for where you are in your fertility journey? If you have been trying for a little longer or are trying after the age of 35, you may need a little more support
- Does it work for your budget? Some products are more expensive than others so you may want to look at options and find the best quality option for your budget.
Choosing a prenatal supplement is the perfect starting point to optimise your fertility outcomes. Some people may benefit from adding additional supplements to their regimen depending on where they are in their journey, their medical history, and dietary intake. Remember on your fertility journey, it is not just about the best fertility supplements for women, check out our blog on the best male fertility supplements.
Getting personalised advice can help you to ensure you are taking the best fertility supplements for you to optimise your outcomes.
Author Bio:
Written by Claire Attwood ANutr – Registered Nutritionist
Reviewed by Ro Huntriss MSc RD, Consultant Dietitian and Founder of Fertility Dietitian UK.
Reviewed April 2026
Medical Disclaimer: This blog is intended for general educational purposes only and does not constitute medical advice. It should not be used as a substitute for personalised guidance, diagnosis, or treatment from a qualified healthcare professional.
Sources and references
- Schaefer E, Nock D. The Impact of Preconceptional Multiple-Micronutrient Supplementation on Female Fertility. Clin Med Insights Womens Health. 2019 Apr 23;12:1179562X19843868. doi: 10.1177/1179562X19843868. PMID: 31040736; PMCID: PMC6480978.
- Chavarro JE, Rich-Edwards JW, Rosner BA, Willett WC. Use of multivitamins, intake of B vitamins, and risk of ovulatory infertility. Fertil Steril. 2008 Mar;89(3):668-76. doi: 10.1016/j.fertnstert.2007.03.089. Epub 2007 Jul 10. PMID: 17624345; PMCID: PMC2366795.
- Lipovac M, Aschauer J, Imhof H, Herrmann C, Sima M, Weiß P, Imhof M. The effect of micronutrient supplementation on serum anti-Mullerian hormone levels: a retrospective pilot study. Gynecol Endocrinol. 2022 Apr;38(4):310-313. doi: 10.1080/09513590.2022.2028770. Epub 2022 Feb 11. PMID: 35147056.
- Chu J, Gallos I, Tobias A, Tan B, Eapen A, Coomarasamy A. Vitamin D and assisted reproductive treatment outcome: A systematic review and meta-analysis. Hum Reprod [Internet]. 2018 Jan 1 [cited 2021 Jun 18];33(1):65–80.
- Cueto HT, Jacobsen BH, Laursen ASD, Riis AH, Hatch EE, Wise LA, et al. Dietary folate intake and fecundability in two preconception cohorts. Hum Reprod [Internet]. 2022 Apr 1 [cited 2022 Oct 17];37(4):828–3
- Ruder EH, Hartman TJ, Reindollar RH, Goldman MB. Female dietary antioxidant intake and time to pregnancy among couples treated for unexplained infertility. Fertil Steril [Internet]. 2014 Mar [cited 2022 Oct 19];101(3):759–66.
- Ebisch IMW, Thomas CMG, Peters WHM, Braat DDM, Steegers-Theunissen RPM. The importance of folate, zinc and antioxidants in the pathogenesis and prevention of subfertility. Hum Reprod Update [Internet]. 2007 Mar 1 [cited 2022 Oct 19];13(2):163–74.
- Xing M, Gu S, Wang X, Mao G, Mo Z, Lou X, et al. Low Iodine Intake May Decrease Women’s Fecundity: A Population-Based Cross-Sectional Study. Nutrients [Internet]. 2021 Sep 1 [cited 2022 Oct 19];13(9).
- Gaskins AJ, Chiu YH, Williams PL, Ford JB, Toth TL, Hauser R, et al. Association between serum folate and vitamin B-12 and outcomes of assisted reproductive technologies. Am J Clin Nutr [Internet]. 2015 Oct 1 [cited 2022 Oct 19];102(4):943.
- Carboni L. Active Folate Versus Folic Acid: The Role of 5-MTHF (Methylfolate) in Human Health. Integr Med (Encinitas). 2022 Jul;21(3):36-41. PMID: 35999905; PMCID: PMC9380836.
- Florou P, Anagnostis P, Theocharis P, Chourdakis M, Goulis DG. Does coenzyme Q10 supplementation improve fertility outcomes in women undergoing assisted reproductive technology procedures? A systematic review and meta-analysis of randomized-controlled trials. J Assist Reprod Genet. 2020 Oct;37(10):2377-2387. doi: 10.1007/s10815-020-01906-3. Epub 2020 Aug 7. PMID: 32767206; PMCID: PMC7550497.
- Greff D, Juhász AE, Váncsa S, Váradi A, Sipos Z, Szinte J, Park S, Hegyi P, Nyirády P, Ács N, Várbíró S, Horváth EM. Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. Reprod Biol Endocrinol. 2023 Jan 26;21(1):10. doi: 10.1186/s12958-023-01055-z. PMID: 36703143; PMCID: PMC9878965.
- Zheng X, Lin D, Zhang Y, Lin Y, Song J, Li S, Sun Y. Inositol supplement improves clinical pregnancy rate in infertile women undergoing ovulation induction for ICSI or IVF-ET. Medicine (Baltimore). 2017 Dec;96(49):e8842. doi: 10.1097/MD.0000000000008842. PMID: 29245250; PMCID: PMC5728865.
- Trop-Steinberg S, Gal M, Azar Y, Kilav-Levin R, Heifetz EM. Effect of omega-3 supplements or diets on fertility in women: A meta-analysis. Heliyon. 2024 Apr 6;10(8):e29324. doi: 10.1016/j.heliyon.2024.e29324. PMID: 38628754; PMCID: PMC11019195.
