Fertility is a journey, and navigating the vast array of supplements available can be overwhelming. As a Fertility Dietitian in the UK, I often get asked about the best fertility supplements and prenatal vitamins. In this blog, I will provide evidence-based recommendations on the best fertility supplements in 2025 to help you make informed decisions. Let’s dive in!
The best prenatal vitamins
If you’re trying to conceive, a high-quality prenatal supplement is one of the best investments you can make. Prenatal supplements are multivitamins that contain essential nutrients to support fertility. We recommend starting a prenatal supplement three months before trying to conceive to enhance egg quality and fill any nutrient gaps.
Why take a prenatal supplement
Evidence shows that taking a prenatal supplement alongside a fertility-supporting diet can significantly boost your chances of conception. Here are some benefits:
- Reduce Nutrient Deficiencies: Prenatal supplements help cover any nutritional gaps, lowering levels of certain nutrients linked to unexplained infertility and increased time to pregnancy.
- Strengthen Antioxidant Defences: They protect eggs from damage.
- Reduce Ovulatory Problems: Ovulatory issues are a common cause of infertility, and supplements can help mitigate this.
- Support AMH Levels: Anti-Müllerian Hormone (AMH) levels, a marker of ovarian reserve, can be supported with the right nutrients.
How to choose the best prenatal fertility supplement for you
With many products on the market, it’s important to choose one that fits your needs. Here’s what to look for:
- Vitamin D: Lower levels are associated with infertility. Ensure your supplement contains at least 10mcg.
- Folate or Folic Acid: Critical for DNA production, egg quality, and implantation. Look for at least 400mcg.
- Antioxidants: Look for vitamins C, E, and selenium to combat oxidative stress.
- Zinc: Essential for the egg maturation process.
- Iodine: Important for thyroid function and reducing the risk of unexplained infertility.
- B Vitamins: Vitamins B12 and B6 are crucial, as insufficient levels are common in infertile women.
Which is the best prenatal vitamin to buy?
Disclosure: All supplement recommendations in this guide are based on clinical expertise and current fertility nutrition research. Some links are affiliate-based, but this does not influence which products are included. Discount codes are offered for your benefit, with no added cost to you.
There are many different products on the market, but our top recommendations include
- Proceive – Contains high levels of fertility-supporting ingredients, including 400mcg of methyl folate. Great for those starting their journey.
Why we like it: A robust all-rounder that offers high levels of key nutrients in absorbable forms.
- Proceive Max – Offers higher nutrient amounts, ideal for those seeking maximum support.
Why we like it: Excellent for women over 35 and those trying to conceive for a year or more, due to its higher micronutrient content and is often recommended in our clinic.
Use the code DIETITIANRO15 to get 15% off products in the Proceive range.
- Pregnacare – Includes 400mcg of folic acid and 10mcg of vitamin D, along with 17 other fertility-supporting nutrients.
Why we like it: Affordable and accessible.
- Pregnacare Max – Contains methylfolate and omega-3 fatty acids, offering a comprehensive 2-in-1 solution.
Why we like it: Combines essential micronutrients with omega-3
- Zita West Vitafem – Provides a thorough mix of nutrients, including 400mcg of methylfolate, B vitamins, zinc, selenium, and more.
Why we like it: high quality, comprehensive, and balanced formula
- Artah enhanced fertility – a comprehensive supplement designed to support you before, during and after pregnancy.
Why we like it: It may be suitable for individuals seeking a broader, nutrient-dense formula that includes antioxidants like CoQ10 and NAC.
Use the code RoHuntrissNutrition to get 15% off all Artah products.
- Wild Nutrition fertility support – A natural, whole-food-based supplement designed to mirror the way your body absorbs nutrients from food.
Why we like it: Ideal for those looking for natural food-grown nutrient support.
- MyOva Preconception – Designed to support women with hormonal imbalances and PCOS, featuring inositol, NAC, beta-carotene, and methylfolate.
Why we like it: Excellent option for PCOS and hormone balance, with high-dose inositol and methylfolate.
Use SEREHEALTHY15 for 15% off all MyOva products
- OVUM Time to Conceive – Formulated by doctors, OVUM combines CoQ10, NAC, alpha-lipoic acid, and methylfolate to support fertility. 20% of profits are reinvested into independent fertility research and education.
Why we like it: A science-led, antioxidant-focused formula that reinvests profits into fertility research.
Use the code DIETITIANRO for 15% off all OVUM products
Methyl folate vs folic acid
Prenatal supplements may contain vitamin B9 in its natural form (methylfolate) or its synthetic form (folic acid). A risk factor for neural tube defects is having low folate levels. Both forms increase blood folate levels, which corrects the risk factor of folate deficiency, but currently, public health guidance recommends folic acid to reduce the risk of neural tube defects. If your prenatal supplement contains methylfolate, you can safely add 400 mcg of folic acid; always discuss with your healthcare provider or fertility expert beforehand.
Methylfolate may be considered in some situations, for example, people who carry a mutation in the MTHFR gene may not be able to convert folic acid to the active form of folate in the body as efficiently as those without the mutation. There is also some evidence to suggest that methylfolate could be explored in cases of recurrent miscarriage or recurrent implantation failure. However, you should discuss this with your healthcare provider. This information is not a substitute for individualised medical advice.
- Holland and Barrett Folic Acid (400ug)
- Folic acid 400 mcg (contains Vitamin B12)
Our other top fertility supplement recommendations
For specific needs, other supplements might be beneficial. Here are our top recommendations to help you on your fertility journey.
The best CoQ10 supplements for fertility
If you are over the age of 35, adding a Coenzyme Q10 supplement to your regimen can be one of the best fertility supplement choices you can make. CoQ10 is crucial for energy production and can help support egg production, maturation, and quality.
- Zita West Kaneka Ubiquinol – A premium CoQ10 supplement delivering 200mg per day of Kaneka Ubiquinol; the body-ready, active form of CoQ10 and is thought to be up to 70% more bioavailable than ubiquinone.
- MicroCell CoQ10 – A high-strength supplement delivering 200mg of ubiquinone, the standard form of CoQ10.
Fertility supplements for PCOS
For those with Polycystic Ovary Syndrome (PCOS), myoinositol can be particularly beneficial. It helps regulate menstrual cycles, restore ovulation, improve egg and embryo quality, and enhance clinical pregnancy rates. With regards to doses, 4g/day of myo-inositol alone or a combination of myo-inositol and d-chiro inositol in a 40:1 ratio can support outcomes.
This supplement has also been shown to increase clinical pregnancy rate in women undergoing IVF by improving egg and embryo quality and improving response to ovarian stimulation.
Here are our top recommendations for the best myoinositol for PCOS and to support IVF outcomes:
Myoinositol alone:
- Zita West inositol and folate – This supplement provides 4g of myoinositol and 200 mcg of methyl folate.
- MyOva – contains 4g of myoinositol alongside 200 mcg of folate, a small amount of vitamin B6, and chromium in tablet form.
Use SEREHEALTHY15 for 15% off all MyOva products
Myoinositol + D chiro inositol in a 40:1 ratio:
- Intimate Rose Inositol D Chiro Inositol Tablets – a Myoinositol & D Chiro Inositol complex providing a 40:1 ratio alongside vitamin D and ashwagandha.
Use code ROHUNTRISS for 10% off all Intimate Rose products
The best omega-3 supplements for fertility
Omega-3 fatty acids are essential fats that must be consumed through diet or supplements. They are beneficial for supporting ovarian reserve, egg quality, and improving IVF outcomes. Omega-3 supplements are particularly important if you do not consume 1-2 portions of oily fish weekly. Research indicates that even those who consume omega-3 through food can benefit from supplementation.
We recommended to consume around 500-1000mg per day. .
- Wild Nutrition Food-Grown Pure Strength Omega 3 – high strength EPA and DHA supplement, offering a total of 1200mg of EPA and DHA.
- Proceive omega 3: – Offers a total of 1100mg of EPA and DHA. Use the code DIETITIANRO15 to get 15% off
- Zita West – Vital DHA: This higher strength version contains 1072mg of omega-3, with 50% DHA and 10% EPA.
- Zita West Ultra Omega 3: Provides 450mg of EPA and DHA.
- Biocare vegan omega: Contains 500mg of EPA and DHA derived from algal oil, ideal for those following a plant-based diet.
The Bottom Line
Choosing the best fertility supplements can be a game-changer on your journey to conception. Always consult with your healthcare provider or a fertility dietitian to tailor the best approach for your specific needs. With the right support and supplements, you are taking control of your journey. You can also explore our meal plans or book a 1:1 consultation for more tailored supplement advice
Written by: Ro Huntriss
Last reviewed: July 2025
